B12 can be bought OTC or over the counter in many countries: Neurobion B1 B6 B12 Ampavit B12 TP B100 Complex Merck Ampavit Cyanocobalamin is a man-made form of vitamin used to treat low levels (deficiency) of this vitamin. Vitamin B12 helps your body use fat and carbohydrates for energy and make new protein. It is also important for normal blood, cells, and nerves. Most people get enough of this vitamin in their diet, but a deficiency may occur in certain health conditions (e.g., poor nutrition, stomach/intestinal problems, infection, cancer). Serious vitamin B deficiency may result in anemia, stomach problems, and nerve damage.
Why is B12 used?
B124u: Anemia due to B12 deficiency conditions; in the complex therapy for iron and posthemorrhagic anemia; aplastic anemia caused by toxic substances and drugs; liver disease (hepatitis, cirrhosis); funicular myelosis; polyneuritis, radiculitis, neuralgia, amyotrophic lateral sclerosis; children cerebral palsy, Down syndrome, peripheral nerve injury; skin diseases (psoriasis, photodermatosis, herpetiformis dermatitis, neurodermatitis); to prevent and treat symptoms of deficiency of vitamin B12 (including the application of biguanide, PASA, vitamin C in high doses); radiation sickness
This the most bio-available form of Vitamin B12. It differentiates from the rest because it has Methyl- group (CH3).
Vitamin B12 benefits your mood, energy level, memory, heart, skin, hair, digestion and more. Vitamin B12 is also an essential vitamin for addressing adrenal fatigue, multiple metabolic functions — including enzyme production, DNA synthesis and hormonal balance — and maintaining healthy nervous and cardiovascular systems.
+Helps Maintain Energy Levels. …
+Prevents Memory Loss and Lowers Risk of Neurodegenerative Disease. …
+Boosts Mood and Helps the Nervous System to Properly Function. …
+Plays a Role in Maintaining Heart Health. …
+Needed for Healthy Skin and Hair. …
+Aids in Digestion. …
+Needed for a Healthy Pregnancy.
Vitamin B12 is a water soluble vitamin essential in the human diet. There are 12 different types of B-Vitamin,
Vitamin B12 benefits the central nervous system in many important ways: It helps maintain the health of nerve cells — including those needed for neurotransmitter signaling — and helps form the protective covering of nerves, called the cell’s myelin sheath. This means that when vitamin B12 levels are low, almost every cognitive function can suffer.
Vitamin B12, sometimes also called Methylcobalamin, also helps with digestion and heart health, so a deficiency can lead to both digestive disorders and an increased risk for heart disease.
Below is a brief research on Methylcobalamin.
Methylcobalamin. B12, also known as cobalamin, naturally exists in the body in the form of Methylcobalamin.
Only adenosylcobalamin (AdeCbl) and methylcobalamin (MetCbl) are active within the human body. You’ll find MetCbl mainly in your blood plasma, cytosol cells, and certain body fluids (like cerebral spinal fluid), and AdeCbl in cellular tissues where it is stored in the mitochondria. In fact, the benefits of B12 all boil down to two biochemical reactions:
The conversion of methylmalonyl-coenzyme A to succinylcholine coenzyme A (by methylmalonyl-CoA mutase, with adenosylcobalamin as a cofactor), and the remethylation of homocysteine to methionine (with methylcobalamin being a cofactor for methionine synthase).
(also Mecobalamin, MeCbl, MetCbl, MetB12, MeB12, or Methyl B12)
Methylcobalamin, the kingpin, one of the two active, natural forms of B12. It helps reduce homocysteine concentrations and generates SAMe (S-adenosyl methionine), the most important methyl donor in your body, supplying methyl groups for crucial chemical reactions to help maintain your health.
Where methyl B12 shows its greatest utility is with people suffering form degenerative neurological symptoms, where it’s often the only promising treatment. It bypasses several potential issues in the absorption cycle and helps relieve or completely reverse symptoms.
High doses of methylcobalamin have been used to treat multiple sclerosis (improved visual and auditory symptoms, not motor ones), amytropic lateral sclerosis, Parkinson’s, and may help regenerate nerves and treat peripheral neuropathies. People with Alzheimer’s noticed an improvement in memory and intellectual function when given this form of B12.
In fact, MetCbl is so effective — in numerous areas — that it is used almost exclusively in Japan to treat B12 deficiency.
Cyanocobalamin: it takes more than 48 hours for cyanocobalamin B12 to eventually convert to usable methylcobalamin, and even then only a small amount is converted.
Hydroxocobalamin is also an inactive form of B12, but it is better than cyanocobalamin because it doesn’t contain any cyanide, therefore bypassing the need for decyanation and preserving the glutathione. It also has to be reduced from state +3 to +1 before it can become either Methylcobalamin or AdeCobalamin.
Biotin B7 plays a major role in helping the human body convert food into usable energy (also referred to as vitamin H and B7). This B complex vitamin is plentiful in a wide range of foods including nuts, legumes, cauliflower, whole grains, mushrooms, eggs, oysters, and organ meats.
Though biotin is present in a number of foods, not everyone can consume enough of them on a regular basis. When this happens, taking a biotin supplement is a smart way to take advantage of these 12 impressive benefits of biotin.
1. Thickens Hair
One of the biggest benefits of biotin is that it helps stimulate hair growth, causing hair to thicken and appear more lustrous. Biotin can also help hair look healthier while growing more quickly and sustainably. This is good news for healthy people who want their hair to look its best, as well as those with health issues that lead to lackluster hair.
While people with healthy digestive systems can absorb some biotin simply by eating a healthy diet every day, those who suffer from digestive disorders struggle to absorb adequate vitamins and nutrients. Those diagnosed with malabsorption problems like leaky gut syndrome, celiac disease, and Crohn’s disease often require elevated nutrient levels in order to receive the vitamins and minerals they need to stay healthy. Along with giving healthy people an extra boost, biotin supplements can help people who struggle with nutrient deficiencies to improve their unhealthy hair loss and dry, brittle hair.
2. Improves Skin
For many people, a Vitamin H deficiency can also lead to significant problems with their skin’s inner health and outer appearance. Dry, itchy skin is one of the most common issues, although more serious conditions like acne and psoriasis can also arise. Keep in mind that if you don’t nourish your skin from the inside out, resulting hormonal issues can result in serious skin problems.
In most cases, a biotin supplement can correct the issue, improving skin and helping to create a youthful glow. To address biotin deficiencies, it’s important to access the vitamin in the most effective way. While many topical skin and hair products include added biotin, you can’t usually absorb this B complex vitamin through skin or hair cells. Instead, you must ingest a biotin supplement to receive all of the vitamin’s benefits.
3. Strengthens Nails
Along with improving hair and skin, biotin is known for its ability to strengthen nails. In fact, higher doses of biotin have resulted in significant nail health improvement. Studies have shown that those who take a biotin supplement can thicken their nails by up to 25 percent and decrease the amount of nail splitting and breakage they endure. Trial studies also have shown that an impressive 91 percent of participants experience improved nail strength when taking a biotin supplement.
4. Rebuilds Tissues
Neither muscle nor tissue lasts forever, and your body relies on B vitamins to help rebuild after tissues break down or muscles sustain damage. Biotin is one of the components necessary for rebuilding muscle strength and helping tissues grow. This vitamin also has a key role in alleviating muscle and joint inflammation, aches, and pains. If you continually experience joint pain or struggle with muscle strength, a biotin supplement might be just what you need to help your tissues rebuild.
5. Assists With Cell Growth
In addition to making you look great, biotin also helps with some of your body’s most essential functions. One of vitamin H’s primary roles is to regulate the formation of DNA. This ensures that the genetic information in each cell works properly and replicates correctly. Though strong cell development is always important, it’s especially critical when your cells are dividing rapidly, such as during pregnancy.
Keep in mind that biotin supplements provide you with an ample supply of this water-soluble vitamin. Once it travels through your bloodstream, however, your body eliminates any excess biotin. That means your body never builds up a toxic reserve of this vitamin, and overconsuming it is nearly impossible.
6. Promotes Fetal and Child Development
Since biotin is necessary for many bodily functions, it’s especially important for pregnant women supporting a new life. In fact, a recent study shows that many pregnant women don’t receive enough biotin naturally on a daily basis. Since this has led to serious birth defects, many doctors recommend that pregnant women supplement their regular healthy diets with additional biotin. For many pregnant women, taking additional biotin is as important as taking folic acid for ensuring baby health, encouraging fetal development, and minimizing pregnancy complications.
In some cases, new mothers don’t provide enough biotin in their breast milk, leading to a biotin deficiency in their babies. Young children with allergies to or a distaste for foods high in biotin are also at risk of developing a deficiency. A biotin supplement can easily remedy low levels of biotin in new mothers, babies, and children. Expecting and new mothers should talk with a physician before taking a biotin supplement while pregnant or nursing or before giving biotin to babies and children.
7. Protects Your Brain
Along with the other B complex vitamins, biotin keeps your nervous system in working order by assisting with neurotransmitter activity and helping with nerve signals. Together, B vitamins also protect your brain, improve your memory, and help form a defense against cognitive issues and neurodegenerative disorders. Along with preventing dementia and Alzheimer’s disease, biotin and the other B vitamins can help you better your concentration and keep a positive outlook.
8. Stabilizes Blood Sugar
One of the most beneficial ways biotin can affect people is by stabilizing blood sugar. For diabetics or those who struggle with maintaining a healthy blood sugar level, biotin can be particularly helpful. Studies have shown that this B complex vitamin has the power to lower blood glucose levels in people with both Type 1 and Type 2 diabetes by stimulating the secretion of insulin.
Some diabetics also suffer from nerve damage due to enzyme buildup. Since biotin is necessary for certain enzyme activity, low levels of this vitamin can lead to dangerous levels of buildup. A biotin supplement can get enzyme activity back on track and help some diabetics prevent additional nerve damage.
9. Boosts Energy and Mood
One of biotin’s primary functions is its ability to metabolize carbohydrates, proteins, and fats. This vitamin also functions as a coenzyme and aids in synthesizing fatty acids and certain amino acids. Without the B complex vitamins, your body can’t use the energy that your body consumes.
Since biotin and the other B vitamins play a big part in converting nutrients into fuel that your body can access, a lack of biotin can cause you to feel a serious slump in energy. In fact, it can also lead to feelings of fatigue, mood swings, and even digestive issues. If you don’t receive a steady supply of biotin from your daily diet, a supplement can help you harness the energy you’re missing and help you get your mood back on a positive track.
10. Supports Thyroid Function
In addition to your nervous system, your body relies on key glands to normalize functions and keep you going. Biotin is necessary for maintaining appropriate thyroid activity and regulating sleep, hunger, energy, and even pain. If your body has trouble controlling these basic functions or if you experience weight gain, trouble sleeping, or constant fatigue, additional biotin can help with thyroid regulation.
9. Lowers Cholesterol
High cholesterol is much more than just a large number on a chart. High levels of low-density lipoprotein, better known as the bad cholesterol, can actually lead to heart disease. This in turn can increase your chances of having a stroke or a heart attack. If you struggle to maintain healthy LDL levels, biotin may be able to help get them within a reasonable range.
Research has shown that this vitamin can help lower LDL levels while increasing levels of high-density lipoprotein, otherwise known as the good cholesterol. Since B complex vitamins are also important in reducing inflammation and plaque buildup in arteries, biotin can also help lower the risk of heart attacks and strokes. Diabetics and others who are particularly susceptible to heart disease will find this benefit particularly helpful.
12. Aids in Weight Loss
Along with boosting metabolism, biotin can also aid in weight loss. Essentially, consuming or ingesting biotin elevates your resting rate of metabolism. As this vitamin increases your metabolism, it can help accelerate weight loss, especially when paired with chromium.
If you’re considering taking a biotin supplement to help with weight loss, keep in mind that this B complex vitamin doesn’t act as a diet pill. Instead, it helps your body speed up the weight loss process as you consume a healthy diet and get regular exercise.
The information on this website is general and you should always ask your Doctor or a health care professional before taking any form of medication albeit Vitamins or Supplements; regardless of the status. OTC or over the counter does not necessarily mean its safe, always seek advice first and read the information leaflet provided.
The above information has been compiled using other sources/websites and therefore we are not responsible for the above.
Readers are advised:
To do their own research and make decisions in partnership with their health care provider. If you are pregnant, nursing, have a medical condition or are taking any medication, please consult your physician. Nothing you read here should be relied upon to determine dietary changes, a medical diagnosis or courses of treatment.
FDA Disclaimer: The advice & statements on this blog have not been evaluated by the Food & Drug Administration.
Any information on this blog is not intended to diagnose, treat, cure, or prevent any disease.